The School of Science and Technology is one of Hellenic Open University's first four Schools, founded according to Act Ν.2552/97. The School offers education in Natural Science, Mathematics, Computer Science, Environmental Science, Construction Design and Management.

• consists of 13 faculty members
  
• offers 12 study programs (2 undergraduate and 10 postgraduate) through 104 courses
• employs more than 600 tutors
• enrolls approximately 2025 new students each year
• has 9829 undergraduate and postgraduate students, 49 PhD candidates and 9 postdoctoral researchers
• has awarded >9500 bachelor and master titles, as well as 23 doctoral degrees.